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A platform for research: civil engineering, architecture and urbanism
Predicting lead relative bioavailability in peri-urban contaminated soils using in vitro bioaccessibility assays
In this study, lead (Pb) bioaccessibility was assessed in peri-urban contaminated soils using a variety of established in vitro assays. Bioaccessibility data was then used to predict Pb relative bioavailability (RBA) using published in vivo-in vitro regression models in order to compare calculated estimates and measured values. Lead bioaccessibility varied depending on the in vitro methodology employed with the relative bioavailability leaching procedure (RBALP) and in vitro gastrointestinal (IVG) assays providing more conservative Pb bioaccessibility values compared to those determined using PBET, UBM and Rel-SBRC-I assays. When Pb RBA was calculated, predicted values using PBET-G and UBM-G data were similar to measured Pb RBA values. However, Pb RBA was over-estimated by 1.6–5.5- and 2.6–6.6-fold when data and regression models from RBALP and IVG-G assays were employed.
Predicting lead relative bioavailability in peri-urban contaminated soils using in vitro bioaccessibility assays
In this study, lead (Pb) bioaccessibility was assessed in peri-urban contaminated soils using a variety of established in vitro assays. Bioaccessibility data was then used to predict Pb relative bioavailability (RBA) using published in vivo-in vitro regression models in order to compare calculated estimates and measured values. Lead bioaccessibility varied depending on the in vitro methodology employed with the relative bioavailability leaching procedure (RBALP) and in vitro gastrointestinal (IVG) assays providing more conservative Pb bioaccessibility values compared to those determined using PBET, UBM and Rel-SBRC-I assays. When Pb RBA was calculated, predicted values using PBET-G and UBM-G data were similar to measured Pb RBA values. However, Pb RBA was over-estimated by 1.6–5.5- and 2.6–6.6-fold when data and regression models from RBALP and IVG-G assays were employed.
Predicting lead relative bioavailability in peri-urban contaminated soils using in vitro bioaccessibility assays
Juhasz, Albert L. (author) / Smith, Euan (author) / Weber, John (author) / Rees, Matthew (author) / Kuchel, Tim (author) / Rofe, Allan (author) / Sansom, Lloyd (author) / Naidu, Ravi (author)
Journal of Environmental Science and Health, Part A ; 48 ; 604-611
2013-05-01
8 pages
Article (Journal)
Electronic Resource
English
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