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Bioactive PMMA-based cement incorporated with nano-sized rutile particles

Hashimoto, M. / Takadama, H. / Mizuno, M. / Kokubo, T. / Goto, K. / Nakamuro, T.

Bioactive bone cement with mechanical properties higher than that of commercial polymethylmethacrylate (PMMA) bone cement are strongly desired to be developed. In the present study, PMMA-based cement incorporated with nano-sized rutile particles was prepared. The PMMA-based cement (rutile content was 50 wt-%) shows the compressive strength (136 MPa) higher than that of commercial PMMA bone cement (88 MPa). The hardened cement formed apatite on the surface in a simulated body fluid within 3 days. Therefore, this PMMA-based cement incorporated with rutile particles might be useful as cement for fixation of prostheses as well as self-setting bone substitutes, because of its high apatite forming ability and mechanical strength.

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Bioactive PMMA-based cement incorporated with nano-sized rutile particles

Hashimoto, M. / Takadama, H. / Mizuno, M. / Kokubo, T. / Goto, K. / Nakamuro, T.

Bioactive bone cement with mechanical properties higher than that of commercial polymethylmethacrylate (PMMA) bone cement are strongly desired to be developed. In the present study, PMMA-based cement incorporated with nano-sized rutile particles was prepared. The PMMA-based cement (rutile content was 50 wt-%) shows the compressive strength (136 MPa) higher than that of commercial PMMA bone cement (88 MPa). The hardened cement formed apatite on the surface in a simulated body fluid within 3 days. Therefore, this PMMA-based cement incorporated with rutile particles might be useful as cement for fixation of prostheses as well as self-setting bone substitutes, because of its high apatite forming ability and mechanical strength.

Bioactive PMMA-based cement incorporated with nano-sized rutile particles

Hashimoto, M. / Takadama, H. / Mizuno, M. / Kokubo, T. / Goto, K. / Nakamuro, T.

Bioactive bone cement with mechanical properties higher than that of commercial polymethylmethacrylate (PMMA) bone cement are strongly desired to be developed. In the present study, PMMA-based cement incorporated with nano-sized rutile particles was prepared. The PMMA-based cement (rutile content was 50 wt-%) shows the compressive strength (136 MPa) higher than that of commercial PMMA bone cement (88 MPa). The hardened cement formed apatite on the surface in a simulated body fluid within 3 days. Therefore, this PMMA-based cement incorporated with rutile particles might be useful as cement for fixation of prostheses as well as self-setting bone substitutes, because of its high apatite forming ability and mechanical strength.

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Title:

Bioactive PMMA-based cement incorporated with nano-sized rutile particles

Contributors:

Hashimoto, M. (author) / Takadama, H. (author) / Mizuno, M. (author) / Kokubo, T. (author) / Goto, K. (author) / Nakamuro, T. (author)

Published in:

Bioceramics 18, ISCM, International Symposium on Ceramics in Medicine, the Annual Meeting of the International Society for Ceramics in Medicine, 18 ; 797-800

Key Engineering Materials ; 309-311

Publication date:

2006

Size:

4 Seiten, 4 Bilder, 6 Quellen

ISBN:

ISSN:

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.309-311.797

Type of media:

Conference paper

Type of material:

Print

Language:

English

Keywords:

Abbindung , Anwendung in der Medizin , Apatit , Bioaktivität , Druckfestigkeit , Fixierung (Befestigung) , Knochenzement , Körperflüssigkeit , Nanopartikel , Polymethylmethacrylat , Prothese , Rutil , Simulation

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