A platform for research: civil engineering, architecture and urbanism
A platform for research: civil engineering, architecture and urbanism
Addition of cohesion promotors to calcium phosphate cements
CPCs (calcium phosphate cements) have been developed since 1983. They are suitable for the repair and reconstruction of bone because they are osteotransductive, i.e. after implantation in bone defects they are rapidly integrated into the bone structure, after which they are transformed into new bone by the cellular activity of osteoblasts and osteoclasts which take care of the local bone remodelling. Many CPCs pastes tend to disintegrate upon early contact with blood or other aqueous (body) fluids, which inhibits the use of these materials for clinical use as for bone repair, reconstruction and augmentation. In studies on CPCs based on tetracalcium phosphate and dicalcium hydrogen phosphate others have suggested to use sodium alginate, cellulose derivatives or chitosan derivatives dissolved in the cement liquid for improving the cohesion of CPC pastes. In this study 10 other organic compounds were shown to act as cohesion promoters in the case of CPCs based on alpha-tertiary calcium phosphate as the main active ingredient.
Addition of cohesion promotors to calcium phosphate cements
CPCs (calcium phosphate cements) have been developed since 1983. They are suitable for the repair and reconstruction of bone because they are osteotransductive, i.e. after implantation in bone defects they are rapidly integrated into the bone structure, after which they are transformed into new bone by the cellular activity of osteoblasts and osteoclasts which take care of the local bone remodelling. Many CPCs pastes tend to disintegrate upon early contact with blood or other aqueous (body) fluids, which inhibits the use of these materials for clinical use as for bone repair, reconstruction and augmentation. In studies on CPCs based on tetracalcium phosphate and dicalcium hydrogen phosphate others have suggested to use sodium alginate, cellulose derivatives or chitosan derivatives dissolved in the cement liquid for improving the cohesion of CPC pastes. In this study 10 other organic compounds were shown to act as cohesion promoters in the case of CPCs based on alpha-tertiary calcium phosphate as the main active ingredient.
Addition of cohesion promotors to calcium phosphate cements
Khairoun, I. (author) / Driessens, F.C.M. (author) / Boltong, M.G. (author) / Planell, J.A. (author) / Wenz, R. (author)
Biomaterials ; 20 ; 393-398
1999
6 Seiten, 12 Tabellen, 33 Quellen
Article (Journal)
English
Sodium Phosphate-Derived Calcium Phosphate Cements
| Online Contents | 1995
Sodium phosphate-derived calcium phosphate cements
| Tema Archive | 1995
Sodium Phosphate-Derived Calcium Phosphate Cements
| British Library Online Contents | 1995