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Continuous Countercurrent Extractive Biocatalysis in Aqueous Surfactant Two‐Phase Systems
To evaluate the possibility of performing extractive biocatalysis in continuous mode, the hydrolysis of penicillin G in a micellar solution containing the nonionic surfactant Tergitol NP‐7 was chosen as model system. While the product phenylacetic acid distributes into the micellar phase, 6‐aminopenicillanic acid moves preferably into the aqueous phase. The yield in the continuous multi‐step process was higher in comparison to equivalent batch systems. Overall, the results demonstrate the suitability of aqueous surfactant two‐phase systems for continuous biocatalytic reactive extraction processes.
Continuous Countercurrent Extractive Biocatalysis in Aqueous Surfactant Two‐Phase Systems
To evaluate the possibility of performing extractive biocatalysis in continuous mode, the hydrolysis of penicillin G in a micellar solution containing the nonionic surfactant Tergitol NP‐7 was chosen as model system. While the product phenylacetic acid distributes into the micellar phase, 6‐aminopenicillanic acid moves preferably into the aqueous phase. The yield in the continuous multi‐step process was higher in comparison to equivalent batch systems. Overall, the results demonstrate the suitability of aqueous surfactant two‐phase systems for continuous biocatalytic reactive extraction processes.
Continuous Countercurrent Extractive Biocatalysis in Aqueous Surfactant Two‐Phase Systems
Ritter, Eric (author) / Smirnova, Irina (author)
Chemie Ingenieur Technik ; 90 ; 348-357
2018-03-01
10 pages
Article (Journal)
Electronic Resource
English
Biocatalysis Meets Systems Biotechnology
| Wiley | 2010
| Online Contents | 1994
| British Library Online Contents | 1994