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From Microbial Succinic Acid Production to Polybutylene Bio‐Succinate Synthesis
A simplified and scalable one‐pot process for the anaerobic production of succinic acid using a metabolically engineered Corynebacterium glutamicum strain is demonstrated. With targeted bioprocess optimization, succinic acid titer of 78 g L−1 and yield of 1.41 molSAmolGLC−1 were achieved. Succinic acid was recovered from the neutral fermentation broth by electrochemically induced crystallization and applied for polybutylene bio‐succinate synthesis using a biocompatible zinc catalyst. Except for a slight color change, the final biopolymer was comparable to the polymer from commercial precursors.
From Microbial Succinic Acid Production to Polybutylene Bio‐Succinate Synthesis
A simplified and scalable one‐pot process for the anaerobic production of succinic acid using a metabolically engineered Corynebacterium glutamicum strain is demonstrated. With targeted bioprocess optimization, succinic acid titer of 78 g L−1 and yield of 1.41 molSAmolGLC−1 were achieved. Succinic acid was recovered from the neutral fermentation broth by electrochemically induced crystallization and applied for polybutylene bio‐succinate synthesis using a biocompatible zinc catalyst. Except for a slight color change, the final biopolymer was comparable to the polymer from commercial precursors.
From Microbial Succinic Acid Production to Polybutylene Bio‐Succinate Synthesis
Tenhaef, Niklas (author) / Hermann, Alina (author) / Müller, Moritz Fabian (author) / Görtz, Jonas (author) / Marienhagen, Jan (author) / Oldiges, Marco (author) / Wiechert, Wolfgang (author) / Bott, Michael (author) / Jupke, Andreas (author) / Hartmann, Laura (author)
Chemie Ingenieur Technik ; 95 ; 587-595
2023-04-01
9 pages
Article (Journal)
Electronic Resource
English
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