A platform for research: civil engineering, architecture and urbanism
A platform for research: civil engineering, architecture and urbanism
Acute effects of exposure to vapors of 3‐methyl‐1‐butanol in humans
The secondary alcohol 3‐methyl‐1‐butanol (3MB, isoamyl alcohol) is used, for example, as a solvent in a variety of applications and as a fragrance ingredient. It is also one of the microbial volatile organic compounds (MVOCs) found in indoor air. There are little data on acute effects. The aim of the study was to assess the acute effects of 3MB in humans. Thirty healthy volunteers (16 men and 14 women) were exposed in random order to 1 mg/m3 3MB or clean air for 2 h at controlled conditions. Ratings with visual analogue scales revealed slightly increased perceptions of eye irritation (P = 0.048, Wilcoxon) and smell (P < 0.0001) compared with control exposure. The other ratings were not significantly affected (irritation in nose and throat, dyspnea, headache, fatigue, dizziness, nausea, and intoxication). No significant exposure‐related effects were found in blinking frequency, tear film break‐up time, vital staining of the eye, nasal lavage biomarkers, lung function, and nasal swelling. In conclusion, this study suggests that 3MB is not a causative factor for health effects in damp and moldy buildings.
Acute effects of exposure to vapors of 3‐methyl‐1‐butanol in humans
The secondary alcohol 3‐methyl‐1‐butanol (3MB, isoamyl alcohol) is used, for example, as a solvent in a variety of applications and as a fragrance ingredient. It is also one of the microbial volatile organic compounds (MVOCs) found in indoor air. There are little data on acute effects. The aim of the study was to assess the acute effects of 3MB in humans. Thirty healthy volunteers (16 men and 14 women) were exposed in random order to 1 mg/m3 3MB or clean air for 2 h at controlled conditions. Ratings with visual analogue scales revealed slightly increased perceptions of eye irritation (P = 0.048, Wilcoxon) and smell (P < 0.0001) compared with control exposure. The other ratings were not significantly affected (irritation in nose and throat, dyspnea, headache, fatigue, dizziness, nausea, and intoxication). No significant exposure‐related effects were found in blinking frequency, tear film break‐up time, vital staining of the eye, nasal lavage biomarkers, lung function, and nasal swelling. In conclusion, this study suggests that 3MB is not a causative factor for health effects in damp and moldy buildings.
Acute effects of exposure to vapors of 3‐methyl‐1‐butanol in humans
Ernstgård, L. (author) / Norbäck, D. (author) / Nordquist, T. (author) / Wieslander, G. (author) / Wålinder, R. (author) / Johanson, G. (author)
Indoor Air ; 23 ; 227-235
2013-06-01
9 pages
Article (Journal)
Electronic Resource
English
Acute effects of exposure to vapors of 3‐methyl‐1‐butanol in humans
| Online Contents | 2013
Acute effects of exposure to 1 mg/m3 of vaporized 2‐ethyl‐1‐hexanol in humans
| Wiley | 2010
Acute effects of exposure to 1 mg/m3 of vaporized 2-ethyl-1-hexanol in humans
| Online Contents | 2010
Airway Exposure to E-Cigarette Vapors Impairs Autophagy and Induces Aggresome Formation
British Library Online Contents | 2016
Limited recovery of soil microbial activity after transient exposure to gasoline vapors
| Online Contents | 2016