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This chapter presents in survey form the strengths and strength distributions of particles that are formed as agglomerates of subparticles and places them in the context of the monolithic particles examined earlier. Agglomerate particles exhibit fracture strengths much less than their monolithic analogs as a consequence of two distinctive structural features: large strength‐limiting flaws and fracture planes with fewer and weaker bonds. Such agglomerate particles include commonly encountered pharmaceutical tablets and food particles, and the less commonly encountered catalyst particles. The near‐exponential effects of porosity on agglomerate particle strength are demonstrated. The detailed effects of pharmaceutical tablet shapes, intermediate between spherical and cylindrical particles, are analyzed. The similarity in strength behavior of edible agglomerates, tablets and food, to inedible agglomerates, catalysts and cement, is noted.
This chapter presents in survey form the strengths and strength distributions of particles that are formed as agglomerates of subparticles and places them in the context of the monolithic particles examined earlier. Agglomerate particles exhibit fracture strengths much less than their monolithic analogs as a consequence of two distinctive structural features: large strength‐limiting flaws and fracture planes with fewer and weaker bonds. Such agglomerate particles include commonly encountered pharmaceutical tablets and food particles, and the less commonly encountered catalyst particles. The near‐exponential effects of porosity on agglomerate particle strength are demonstrated. The detailed effects of pharmaceutical tablet shapes, intermediate between spherical and cylindrical particles, are analyzed. The similarity in strength behavior of edible agglomerates, tablets and food, to inedible agglomerates, catalysts and cement, is noted.
Agglomerate Particle Strengths
Cook, Robert F. (author)
Particle Strengths ; 273-302
2023-02-04
30 pages
Article/Chapter (Book)
Electronic Resource
English
Agglomerate , pharmaceuticals , tablets , food , catalysts , porosity , compaction , excipient