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Functionally-modified oligonucleotides and subunits thereof
H:\rbr\nterwoven\NRPortbl\DCCRBR\17718449I.dox-14/09/2018 Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3' and/or 5'-end groups are provided. The disclosed 5 compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
Functionally-modified oligonucleotides and subunits thereof
H:\rbr\nterwoven\NRPortbl\DCCRBR\17718449I.dox-14/09/2018 Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3' and/or 5'-end groups are provided. The disclosed 5 compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
Functionally-modified oligonucleotides and subunits thereof
HANSON GUNNAR J (Autor:in) / WELLER DWIGHT D (Autor:in) / CAI BAO ZHONG (Autor:in) / ZHOU MING (Autor:in)
30.04.2020
Patent
Elektronische Ressource
Englisch
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