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Functionally-modified oligonucleotides and subunits thereof
H:\rbr\nterwoven\NRPortbl\DCCRBR\17718449I.dox-14/09/2018 Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3' and/or 5'-end groups are provided. The disclosed 5 compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
Functionally-modified oligonucleotides and subunits thereof
H:\rbr\nterwoven\NRPortbl\DCCRBR\17718449I.dox-14/09/2018 Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3' and/or 5'-end groups are provided. The disclosed 5 compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
Functionally-modified oligonucleotides and subunits thereof
HANSON GUNNAR J (author) / WELLER DWIGHT D (author) / CAI BAO ZHONG (author) / ZHOU MING (author)
2020-04-30
Patent
Electronic Resource
English
Functionally-modified oligonucleotides and subunits thereof
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