Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
The invention discloses a hydroxyapatite scaffold material with a graphene-modified surface and a preparation method of the hydroxyapatite scaffold material. The preparation method comprises the following steps: (1), at the normal temperature, respectively preparing a Ca(NO3)2.4H2O solution with a certain concentration and a (NH4)2HPO4 solution with a certain concentration; (2), blending the Ca(NO3)2.4H2O solution and the (NH4)2HPO4 solution obtained in the step (1) according to a certain calcium-phosphorus ratio, stirring for reacting, and regulating and controlling pH of reaction liquid by introducing ammonia water in the reaction process; (3), leaving the reactant obtained in the step (2) to stand overnight and removing impurities so as to obtain a hydroxyapatite material; (4), preparing a graphene solution with a certain concentration, adding the hydroxyapatite obtained in the step (3) into the graphene solution and stirring fully; (5), transferring the mixed solution obtained in the step (4) into a hydrothermal reaction kettle, reacting under sealing conditions and freeze-drying, o as to obtain the novel hydroxyapatite material with the graphene-modified surface. The material has better physical and chemical properties and biocompatibility, and can be clinically used for repairing bone defects.
The invention discloses a hydroxyapatite scaffold material with a graphene-modified surface and a preparation method of the hydroxyapatite scaffold material. The preparation method comprises the following steps: (1), at the normal temperature, respectively preparing a Ca(NO3)2.4H2O solution with a certain concentration and a (NH4)2HPO4 solution with a certain concentration; (2), blending the Ca(NO3)2.4H2O solution and the (NH4)2HPO4 solution obtained in the step (1) according to a certain calcium-phosphorus ratio, stirring for reacting, and regulating and controlling pH of reaction liquid by introducing ammonia water in the reaction process; (3), leaving the reactant obtained in the step (2) to stand overnight and removing impurities so as to obtain a hydroxyapatite material; (4), preparing a graphene solution with a certain concentration, adding the hydroxyapatite obtained in the step (3) into the graphene solution and stirring fully; (5), transferring the mixed solution obtained in the step (4) into a hydrothermal reaction kettle, reacting under sealing conditions and freeze-drying, o as to obtain the novel hydroxyapatite material with the graphene-modified surface. The material has better physical and chemical properties and biocompatibility, and can be clinically used for repairing bone defects.
Hydroxyapatite scaffold material with graphene-modified surface and preparation method of hydroxyapatite scaffold material
LIU YANG (Autor:in)
09.12.2015
Patent
Elektronische Ressource
Englisch
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