Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Hydroxyapatite bone-like material and preparation method thereof
The invention discloses a hydroxyapatite bone-like material and a preparation method thereof. The bone-like material comprises hydroxyapatite ceramic particles, a solvent and a dispersing agent, wherein the particle size range of the hydroxyapatite ceramic particles is 0.1-10 microns, and the solid phase content range of the hydroxyapatite ceramic particles is 30-66vol%; the dispersing agent is citrate, polyacrylic acid, ammonium polyacrylate or polyacetylimine; the content of the dispersing agent is 0.1-3% of the mass of hydroxyapatite ceramic particle dry powder; and the bone-like material also comprises trace element substances or medicinal raw materials. The hydroxyapatite bone-like material can be used for preparing a complex and fine micro-scale three-dimensional structure, and does not collapse or break in the forming process; the obtained material can be used for preparing various ceramic special-shaped parts and structural parts and customized products, including medical implants and tissue engineering scaffolds; and the obtained drug-loaded bone-like material can play double roles in repairing bone defects and drug carriers.
本发明公开一种羟基磷灰石仿骨材料及其制备方法。本发明的仿骨材料，包括羟基磷灰石陶瓷颗粒，溶剂，分散剂；所述的羟基磷灰石颗粒粒径范围为0.1‑10µm，其固相含量范围为30‑66vol%；所述的分散剂为柠檬酸盐，聚丙烯酸，聚丙烯酸铵或聚乙酰亚胺；所述的分散剂含量为羟基磷灰石颗粒干粉质量的0.1‑3%，还包括微量元素物质或药物原料药的加入。本发明可制备复杂精细的微尺度三维结构，成型过程中不会发生坍塌或断裂现象，所得材料可用于制备各种陶瓷的异形件及结构件和定制产品，包括医用植入体及组织工程支架，所得载药仿骨材料可发挥修复骨缺损和药物载体的双重作用。
Hydroxyapatite bone-like material and preparation method thereof
The invention discloses a hydroxyapatite bone-like material and a preparation method thereof. The bone-like material comprises hydroxyapatite ceramic particles, a solvent and a dispersing agent, wherein the particle size range of the hydroxyapatite ceramic particles is 0.1-10 microns, and the solid phase content range of the hydroxyapatite ceramic particles is 30-66vol%; the dispersing agent is citrate, polyacrylic acid, ammonium polyacrylate or polyacetylimine; the content of the dispersing agent is 0.1-3% of the mass of hydroxyapatite ceramic particle dry powder; and the bone-like material also comprises trace element substances or medicinal raw materials. The hydroxyapatite bone-like material can be used for preparing a complex and fine micro-scale three-dimensional structure, and does not collapse or break in the forming process; the obtained material can be used for preparing various ceramic special-shaped parts and structural parts and customized products, including medical implants and tissue engineering scaffolds; and the obtained drug-loaded bone-like material can play double roles in repairing bone defects and drug carriers.
本发明公开一种羟基磷灰石仿骨材料及其制备方法。本发明的仿骨材料，包括羟基磷灰石陶瓷颗粒，溶剂，分散剂；所述的羟基磷灰石颗粒粒径范围为0.1‑10µm，其固相含量范围为30‑66vol%；所述的分散剂为柠檬酸盐，聚丙烯酸，聚丙烯酸铵或聚乙酰亚胺；所述的分散剂含量为羟基磷灰石颗粒干粉质量的0.1‑3%，还包括微量元素物质或药物原料药的加入。本发明可制备复杂精细的微尺度三维结构，成型过程中不会发生坍塌或断裂现象，所得材料可用于制备各种陶瓷的异形件及结构件和定制产品，包括医用植入体及组织工程支架，所得载药仿骨材料可发挥修复骨缺损和药物载体的双重作用。
Hydroxyapatite bone-like material and preparation method thereof
一种羟基磷灰石仿骨材料及其制备方法
LIAO JINGJING (Autor:in) / HU YIHE (Autor:in) / ZHANG DOU (Autor:in) / WU XUEWEN (Autor:in) / LEI PENGFEI (Autor:in) / ZHU JIANXI (Autor:in) / ZHANG ZEJIE (Autor:in)
08.10.2021
Patent
Elektronische Ressource
Chinesisch
IPC:
A61L
Verfahren oder Vorrichtungen zum Sterilisieren von Stoffen oder Gegenständen allgemein
,
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL
/
B33Y
ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
,
Additive (generative) Fertigung, d. h. die Herstellung von dreidimensionalen [3D] Bauteilen durch additive Abscheidung, additive Agglomeration oder additive Schichtung, z. B. durch 3D- Drucken, Stereolithografie oder selektives Lasersintern
/
C04B
Kalk
,
LIME
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