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High-strength injectable magnesium phosphate bone cement and preparation method thereof
The invention discloses high-strength injectable magnesium phosphate bone cement and a preparation method thereof. The high-strength injectable magnesium phosphate bone cement comprises solid-phase powder and curing liquid, wherein the ratio of the solid-phase powder to the curing liquid is (1.5-3.5) g: 1mL; the solid-phase powder comprises the following components in parts by weight: 50-90 parts of magnesium phosphate salt and 10-50 parts of hydrophosphate, wherein the magnesium phosphate salt comprises trimagnesium phosphate, and the hydrophosphate salt comprises monopotassium phosphate; and the curing liquid is an aqueous solution. The solid-phase powder and the curing liquid are directly mixed to prepare the high-strength injectable magnesium phosphate bone cement. The bone cement has high compressive strength, good injectability and collapse resistance, can prolong the curing time and reduce heat release in the reaction process, and is suitable for being applied to the fields of osteoporosis vertebral compression fracture, spinal fusion and bone repair of other bearing parts.
本发明公开了一种高强度可注射磷酸镁骨水泥及其制备方法。该高强度可注射磷酸镁骨水泥包括固相粉末和固化液,固相粉末与固化液比例为1.5‑3.5g:1mL;所述固相粉末包括以下重量份组份:磷酸镁盐50‑90份,磷酸氢盐10‑50份;其中所述磷酸镁盐包括磷酸三镁,所述磷酸氢盐包括磷酸二氢钾;所述固化液为水溶液。通过将固相粉末与固化液直接混合制备得到。该骨水泥具有较高的抗压强度,良好的可注射性和抗溃散性,还可以延长固化时间,并降低反应过程中的放热,适用于骨质疏松椎体压缩性骨折、脊柱融合和其他承重部位骨修复领域应用。
High-strength injectable magnesium phosphate bone cement and preparation method thereof
The invention discloses high-strength injectable magnesium phosphate bone cement and a preparation method thereof. The high-strength injectable magnesium phosphate bone cement comprises solid-phase powder and curing liquid, wherein the ratio of the solid-phase powder to the curing liquid is (1.5-3.5) g: 1mL; the solid-phase powder comprises the following components in parts by weight: 50-90 parts of magnesium phosphate salt and 10-50 parts of hydrophosphate, wherein the magnesium phosphate salt comprises trimagnesium phosphate, and the hydrophosphate salt comprises monopotassium phosphate; and the curing liquid is an aqueous solution. The solid-phase powder and the curing liquid are directly mixed to prepare the high-strength injectable magnesium phosphate bone cement. The bone cement has high compressive strength, good injectability and collapse resistance, can prolong the curing time and reduce heat release in the reaction process, and is suitable for being applied to the fields of osteoporosis vertebral compression fracture, spinal fusion and bone repair of other bearing parts.
本发明公开了一种高强度可注射磷酸镁骨水泥及其制备方法。该高强度可注射磷酸镁骨水泥包括固相粉末和固化液,固相粉末与固化液比例为1.5‑3.5g:1mL;所述固相粉末包括以下重量份组份:磷酸镁盐50‑90份,磷酸氢盐10‑50份;其中所述磷酸镁盐包括磷酸三镁,所述磷酸氢盐包括磷酸二氢钾;所述固化液为水溶液。通过将固相粉末与固化液直接混合制备得到。该骨水泥具有较高的抗压强度,良好的可注射性和抗溃散性,还可以延长固化时间,并降低反应过程中的放热,适用于骨质疏松椎体压缩性骨折、脊柱融合和其他承重部位骨修复领域应用。
High-strength injectable magnesium phosphate bone cement and preparation method thereof
一种高强度可注射磷酸镁骨水泥及其制备方法
DAI HONGLIAN (Autor:in) / LIU JIAWEI (Autor:in) / HOU WEN (Autor:in) / GUO JIAXIN (Autor:in) / ZHUANG PENGZHEN (Autor:in)
04.01.2022
Patent
Elektronische Ressource
Chinesisch
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