Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Zinc silicate/tricalcium phosphate ceramic scaffold as well as preparation method and application thereof
The invention belongs to the field of medical materials for bone injury repair, and discloses a zinc silicate/tricalcium phosphate ceramic scaffold as well as a preparation method and application thereof. The preparation method comprises the following steps of: well mixing solid-phase powder and a thickening agent, adding a polyvinyl alcohol aqueous solution, and blending to obtain printing slurry, the solid phase powder comprising zinc silicate powder and beta-tricalcium phosphate powder; and performing 3D printing on the printing slurry to obtain a scaffold blank, and performing gradient drying and sintering on the scaffold blank to obtain the zinc silicate/tricalcium phosphate ceramic scaffold. The zinc silicate/tricalcium phosphate ceramic scaffold prepared by the method is good in fibershape retention, high in three-dimensional connectivity degree and good in mechanical property and osteogenesis and angiogenesis performance, so that tricalcium phosphate ceramic has a wider application prospect.
本发明属于骨损伤修复医用材料领域，公开了一种硅酸锌复合磷酸三钙陶瓷支架及其制备方法和应用。本发明将固相粉体和增稠剂混合均匀后，加入聚乙烯醇水溶液调和，得到打印浆料；所述固相粉体包括硅酸锌粉体、β‑磷酸三钙粉体；将打印浆料进行3D打印，得到支架坯体，支架坯体经过梯度干燥和烧结，得到所述硅酸锌复合磷酸三钙陶瓷支架。本发明制得的硅酸锌/磷酸三钙陶瓷支架纤维保形性好、三维连通程度高，具有良好的力学性能、成骨和成血管性能，使得磷酸三钙陶瓷具有更广阔的应用前景。
Zinc silicate/tricalcium phosphate ceramic scaffold as well as preparation method and application thereof
The invention belongs to the field of medical materials for bone injury repair, and discloses a zinc silicate/tricalcium phosphate ceramic scaffold as well as a preparation method and application thereof. The preparation method comprises the following steps of: well mixing solid-phase powder and a thickening agent, adding a polyvinyl alcohol aqueous solution, and blending to obtain printing slurry, the solid phase powder comprising zinc silicate powder and beta-tricalcium phosphate powder; and performing 3D printing on the printing slurry to obtain a scaffold blank, and performing gradient drying and sintering on the scaffold blank to obtain the zinc silicate/tricalcium phosphate ceramic scaffold. The zinc silicate/tricalcium phosphate ceramic scaffold prepared by the method is good in fibershape retention, high in three-dimensional connectivity degree and good in mechanical property and osteogenesis and angiogenesis performance, so that tricalcium phosphate ceramic has a wider application prospect.
本发明属于骨损伤修复医用材料领域，公开了一种硅酸锌复合磷酸三钙陶瓷支架及其制备方法和应用。本发明将固相粉体和增稠剂混合均匀后，加入聚乙烯醇水溶液调和，得到打印浆料；所述固相粉体包括硅酸锌粉体、β‑磷酸三钙粉体；将打印浆料进行3D打印，得到支架坯体，支架坯体经过梯度干燥和烧结，得到所述硅酸锌复合磷酸三钙陶瓷支架。本发明制得的硅酸锌/磷酸三钙陶瓷支架纤维保形性好、三维连通程度高，具有良好的力学性能、成骨和成血管性能，使得磷酸三钙陶瓷具有更广阔的应用前景。
Zinc silicate/tricalcium phosphate ceramic scaffold as well as preparation method and application thereof
一种硅酸锌复合磷酸三钙陶瓷支架及其制备方法与应用
YE JIANDONG (Autor:in) / YUAN XINYUAN (Autor:in) / LU TELIANG (Autor:in)
08.02.2022
Patent
Elektronische Ressource
Chinesisch
IPC:
C04B
Kalk
,
LIME
/
A61L
Verfahren oder Vorrichtungen zum Sterilisieren von Stoffen oder Gegenständen allgemein
,
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL
/
B28B
Formgeben von Ton oder anderen keramischen Stoffzusammensetzungen, Schlacke oder von Mischungen, die zementartiges Material enthalten, z.B. Putzmörtel
,
SHAPING CLAY OR OTHER CERAMIC COMPOSITIONS, SLAG OR MIXTURES CONTAINING CEMENTITIOUS MATERIAL, e.g. PLASTER
/
B33Y
ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
,
Additive (generative) Fertigung, d. h. die Herstellung von dreidimensionalen [3D] Bauteilen durch additive Abscheidung, additive Agglomeration oder additive Schichtung, z. B. durch 3D- Drucken, Stereolithografie oder selektives Lasersintern
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