Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Preparation method of biological ceramic capable of precisely, controllably and slowly releasing metal ions
The invention relates to a preparation method of biological ceramic capable of precisely and controllably releasing metal ions. The preparation method comprises the following steps: preparing ceramic ingredients, preparing a ceramic blank and sintering to form ceramic, a ceramic green body is prepared from ceramic powder loaded with metal ions or/and added with metal powder, ceramic is formed through high-temperature sintering, metal is oxidized into oxide capable of rapidly releasing the metal ions in liquid, and the effects of inhibiting and killing bacteria and promoting tissue regeneration are achieved; oxides embedded in a matrix are gradually exposed along with ceramic degradation, metal ions are released, and a slow release effect is formed. The metal in the ceramic is converted into the oxide capable of releasing ions by utilizing the high-temperature accelerated oxidation effect of the metal, and the core is to control the components, types, forms and doses of the doped metal, and more importantly, the micropore quantity and forms are regulated and controlled through the pore-forming agent and the sintering temperature; and the degradation performance is regulated and controlled according to the ratio of the degradable ceramic powder to the non-degradable ceramic powder, so that precise long-acting release of metal ions is realized.
本发明涉及一种精准可控缓释金属离子的生物陶瓷制备方法，包括调制陶瓷配料、制备陶瓷坯体和烧结形成陶瓷；采用载金属离子或/和添加金属粉末的陶瓷粉料制备陶瓷坯体，经高温烧结形成陶瓷，金属被氧化成在液体中能快速释放金属离子的氧化物，实现抑菌杀菌及促进组织再生作用；随陶瓷降解其基质内包埋的氧化物逐步显露而释放金属离子，形成缓释作用。本发明利用金属的高温加速氧化作用，使得陶瓷内的金属转化为能释放离子的氧化物，其核心在于除对掺入金属成分、种类、形态和剂量控制外，更重要是通过造孔剂和烧结温度调控微孔量和形态，以及降解与非降解陶瓷粉料的配比调控降解性能，实现金属离子精确长效释放。
Preparation method of biological ceramic capable of precisely, controllably and slowly releasing metal ions
The invention relates to a preparation method of biological ceramic capable of precisely and controllably releasing metal ions. The preparation method comprises the following steps: preparing ceramic ingredients, preparing a ceramic blank and sintering to form ceramic, a ceramic green body is prepared from ceramic powder loaded with metal ions or/and added with metal powder, ceramic is formed through high-temperature sintering, metal is oxidized into oxide capable of rapidly releasing the metal ions in liquid, and the effects of inhibiting and killing bacteria and promoting tissue regeneration are achieved; oxides embedded in a matrix are gradually exposed along with ceramic degradation, metal ions are released, and a slow release effect is formed. The metal in the ceramic is converted into the oxide capable of releasing ions by utilizing the high-temperature accelerated oxidation effect of the metal, and the core is to control the components, types, forms and doses of the doped metal, and more importantly, the micropore quantity and forms are regulated and controlled through the pore-forming agent and the sintering temperature; and the degradation performance is regulated and controlled according to the ratio of the degradable ceramic powder to the non-degradable ceramic powder, so that precise long-acting release of metal ions is realized.
本发明涉及一种精准可控缓释金属离子的生物陶瓷制备方法，包括调制陶瓷配料、制备陶瓷坯体和烧结形成陶瓷；采用载金属离子或/和添加金属粉末的陶瓷粉料制备陶瓷坯体，经高温烧结形成陶瓷，金属被氧化成在液体中能快速释放金属离子的氧化物，实现抑菌杀菌及促进组织再生作用；随陶瓷降解其基质内包埋的氧化物逐步显露而释放金属离子，形成缓释作用。本发明利用金属的高温加速氧化作用，使得陶瓷内的金属转化为能释放离子的氧化物，其核心在于除对掺入金属成分、种类、形态和剂量控制外，更重要是通过造孔剂和烧结温度调控微孔量和形态，以及降解与非降解陶瓷粉料的配比调控降解性能，实现金属离子精确长效释放。
Preparation method of biological ceramic capable of precisely, controllably and slowly releasing metal ions
一种精准可控缓释金属离子的生物陶瓷制备方法
LU XIAO (Autor:in) / LU JIANXI (Autor:in) / FAN CUNYI (Autor:in) / YU SHIYANG (Autor:in) / YAO YE (Autor:in) / YANG LIANG (Autor:in)
10.10.2023
Patent
Elektronische Ressource
Chinesisch
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