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QUINAZOLINE ANALOGS AS RECEPTOR TYROSINE KINASE INHIBITORS
This invention provides quinazoline analogs of Formula (I): where A is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R 3 groups. The invention also includes methods of using compounds of Formula (I) as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
QUINAZOLINE ANALOGS AS RECEPTOR TYROSINE KINASE INHIBITORS
This invention provides quinazoline analogs of Formula (I): where A is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R 3 groups. The invention also includes methods of using compounds of Formula (I) as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
QUINAZOLINE ANALOGS AS RECEPTOR TYROSINE KINASE INHIBITORS
WALLACE ELI (Autor:in) / TOPALOV GEORGE (Autor:in) / LYSSIKATOS JOSEPH (Autor:in) / BUCKMELTER ALEXANDRE (Autor:in) / ZHAO QIAN (Autor:in)
14.09.2017
Patent
Elektronische Ressource
Englisch
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