Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
In utero exposure to organochlorine pesticides and early menarche in the Avon Longitudinal Study of Parents and Children
Epidemiologic data supporting the role of organochlorine pesticides in pubertal development are limited. Using a nested case-control design, serum collected during pregnancy from mothers of 218 girls who reported menarche before 11.5years of age (cases) and 230 girls who reported menarche at or after 11.5years of age (controls) was analyzed for 9 organochlorines and metabolites. We analyzed the association between in utero organochlorine concentrations and early menarche using multivariate logistic regression controlling for mother's age at menarche, or mother's prenatal BMI. We did not observe an association between in utero exposure to HCB, β-HCH, ϒ-HCH, p,p'-DDT, p,p'-DDE, oxychlordane or trans-nonachlor and early menarche. This study is the first to examine the association between in utero exposure to HCB, β-HCH, ϒ-HCH, oxychlordane or trans-nonachlor and early menarche. In utero exposure to organochlorine pesticides does not appear to have a role in the timing of menarche in this study.
In utero exposure to organochlorine pesticides and early menarche in the Avon Longitudinal Study of Parents and Children
Epidemiologic data supporting the role of organochlorine pesticides in pubertal development are limited. Using a nested case-control design, serum collected during pregnancy from mothers of 218 girls who reported menarche before 11.5years of age (cases) and 230 girls who reported menarche at or after 11.5years of age (controls) was analyzed for 9 organochlorines and metabolites. We analyzed the association between in utero organochlorine concentrations and early menarche using multivariate logistic regression controlling for mother's age at menarche, or mother's prenatal BMI. We did not observe an association between in utero exposure to HCB, β-HCH, ϒ-HCH, p,p'-DDT, p,p'-DDE, oxychlordane or trans-nonachlor and early menarche. This study is the first to examine the association between in utero exposure to HCB, β-HCH, ϒ-HCH, oxychlordane or trans-nonachlor and early menarche. In utero exposure to organochlorine pesticides does not appear to have a role in the timing of menarche in this study.
In utero exposure to organochlorine pesticides and early menarche in the Avon Longitudinal Study of Parents and Children
Namulanda, Gonza (Autor:in) / Maisonet, Mildred / Taylor, Ethel / Flanders, W Dana / Olson, David / Sjodin, Andreas / Qualters, Judith R / Vena, John / Northstone, Kate / Naeher, Luke
2016
Aufsatz (Zeitschrift)
Englisch
BKL:
30.00
Naturwissenschaften allgemein: Allgemeines
Prenatal exposure to organochlorine pesticides and infant growth: A longitudinal study
| DOAJ | 2021