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Application of Compaction Equations for Powdered Pharmaceutical Materials
The paper is focused on an analysis of the most frequently used compaction equations for powdered materials such as Heckel equation, Kawakita equation and Cooper-Eaton equation. Compacting powdered materials is accompanied by various mechanisms of densification dependent on the properties of the compressed material, which makes the equation more satisfactory for a certain group of materials and for another groups less so, or makes the equation completely unsuitable. To determine the suitability of the equation experimental measurements have to be implemented on an instrumented laboratory press. Then these obtained data are approximated by the specific compaction equation and use the regression analysis to determine the parameters describing the required material or physical properties of the compressed material.
Application of Compaction Equations for Powdered Pharmaceutical Materials
The paper is focused on an analysis of the most frequently used compaction equations for powdered materials such as Heckel equation, Kawakita equation and Cooper-Eaton equation. Compacting powdered materials is accompanied by various mechanisms of densification dependent on the properties of the compressed material, which makes the equation more satisfactory for a certain group of materials and for another groups less so, or makes the equation completely unsuitable. To determine the suitability of the equation experimental measurements have to be implemented on an instrumented laboratory press. Then these obtained data are approximated by the specific compaction equation and use the regression analysis to determine the parameters describing the required material or physical properties of the compressed material.
Application of Compaction Equations for Powdered Pharmaceutical Materials
Eckert Maroš (author) / Peciar Peter (author) / Krok Alexander (author) / Fekete Roman (author)
2015
Article (Journal)
Electronic Resource
Unknown
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