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Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Peciar Peter / Eckert Maroš / Fekete Roman / Hrnčiar Viliam

This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were created.

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Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Peciar Peter / Eckert Maroš / Fekete Roman / Hrnčiar Viliam

This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were created.

Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Peciar Peter / Eckert Maroš / Fekete Roman / Hrnčiar Viliam

This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were created.

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Title:

Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Contributors:

Peciar Peter (author) / Eckert Maroš (author) / Fekete Roman (author) / Hrnčiar Viliam (author)

Published in:

Journal of Mechanical Engineering, Vol 66, Iss 1, Pp 65-82 (2016)

Publication date:

2016

ISSN:

DOI:

https://doi.org/10.1515/scjme-2016-0012

Type of media:

Article (Journal)

Type of material:

Electronic Resource

Language:

Unknown

Keywords:

compaction equation , tabletting , angle of internal friction , angle of wall friction , Engineering (General). Civil engineering (General) , TA1-2040

Metadata by DOAJ is licensed under CC BY-SA 1.0

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