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Study on ibuprofen/montmorillonite intercalation composites as drug release system

Zheng, J.P. / Luan, L. / Wang, H.Y. / Xi, L.F. / Yao, K.D.

AbstractThe present paper focused on the intercalation of ibuprofen (IBU) into montmorillonite as a sustained release drug carrier. The intercalation compounds were characterized by X-ray diffraction (XRD), Fourier transformed infrared (FT-IR), and thermogravimetric analysis (TGA). The basal spacing of montmorillonite increased from 1.25 nm to 1.57 nm. The decomposition temperature of intercalated IBU was increased to 471 °C. The in vitro release experiments revealed that IBU was released from MMT steadily and pH dependent.

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Study on ibuprofen/montmorillonite intercalation composites as drug release system

Zheng, J.P. / Luan, L. / Wang, H.Y. / Xi, L.F. / Yao, K.D.

AbstractThe present paper focused on the intercalation of ibuprofen (IBU) into montmorillonite as a sustained release drug carrier. The intercalation compounds were characterized by X-ray diffraction (XRD), Fourier transformed infrared (FT-IR), and thermogravimetric analysis (TGA). The basal spacing of montmorillonite increased from 1.25 nm to 1.57 nm. The decomposition temperature of intercalated IBU was increased to 471 °C. The in vitro release experiments revealed that IBU was released from MMT steadily and pH dependent.

Study on ibuprofen/montmorillonite intercalation composites as drug release system

Zheng, J.P. / Luan, L. / Wang, H.Y. / Xi, L.F. / Yao, K.D.

AbstractThe present paper focused on the intercalation of ibuprofen (IBU) into montmorillonite as a sustained release drug carrier. The intercalation compounds were characterized by X-ray diffraction (XRD), Fourier transformed infrared (FT-IR), and thermogravimetric analysis (TGA). The basal spacing of montmorillonite increased from 1.25 nm to 1.57 nm. The decomposition temperature of intercalated IBU was increased to 471 °C. The in vitro release experiments revealed that IBU was released from MMT steadily and pH dependent.

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Title:

Study on ibuprofen/montmorillonite intercalation composites as drug release system

Contributors:

Zheng, J.P. (author) / Luan, L. (author) / Wang, H.Y. (author) / Xi, L.F. (author) / Yao, K.D. (author)

Published in:

Applied Clay Science ; 36 ; 297-301

Publication date:

2007-01-08

Size:

5 pages

ISSN:

DOI:

https://doi.org/10.1016/j.clay.2007.01.012

Type of media:

Article (Journal)

Type of material:

Electronic Resource

Language:

English

Keywords:

Montmorillonite , Intercalation , Ibuprofen , <italic>In vitro</italic> release

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