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Manganese-doped calcium silicate porous ceramic scaffold and preparation method and application thereof
The invention discloses a manganese-doped calcium silicate porous ceramic scaffold and a preparation method and application thereof. The manganese-doped calcium silicate porous ceramic scaffold is a porous structure scaffold prepared by 3D printing integrated molding of calcium silicate ceramic powder containing manganese ions; Mn in the calcium silicate ceramic powder containing the manganese ions occupies the position of part of Ca but does not change the crystalline phase of calcium silicate, wherein the molar ratio of Mn/(Mn + Ca) is 1-10%; and the mechanical properties, degradation performance, biological activity and photothermal performance of the porous ceramic scaffold are regulated by adjusting the doping amount of the manganese ions in the calcium silicate ceramic powder. The manganese-doped calcium silicate porous ceramic scaffold has high porosity, appropriate degradation speed and high mechanical strength, and is especially suitable for application in bone defect repair and photothermal therapy of bone tumors.
本发明公开锰掺杂硅酸钙多孔陶瓷支架及其制备方法和应用。所述锰掺杂硅酸钙多孔陶瓷支架是将含有锰离子的硅酸钙陶瓷粉体通过3D打印一体化成型制备的多孔结构支架；所述含有锰离子的硅酸钙陶瓷粉体中Mn占据部分Ca的位置但未改变硅酸钙的晶相，其中，Mn/（Mn+Ca）的摩尔比例为1‑10%；通过调节硅酸钙陶瓷粉体中锰离子的掺杂量调控多孔陶瓷支架的力学性能、降解性能、生物活性和光热性能。所述锰掺杂硅酸钙多孔陶瓷支架兼具高孔隙率、合适降解速度和高力学强度，尤其适合在骨缺损修复与光热治疗骨肿瘤的应用。
Manganese-doped calcium silicate porous ceramic scaffold and preparation method and application thereof
The invention discloses a manganese-doped calcium silicate porous ceramic scaffold and a preparation method and application thereof. The manganese-doped calcium silicate porous ceramic scaffold is a porous structure scaffold prepared by 3D printing integrated molding of calcium silicate ceramic powder containing manganese ions; Mn in the calcium silicate ceramic powder containing the manganese ions occupies the position of part of Ca but does not change the crystalline phase of calcium silicate, wherein the molar ratio of Mn/(Mn + Ca) is 1-10%; and the mechanical properties, degradation performance, biological activity and photothermal performance of the porous ceramic scaffold are regulated by adjusting the doping amount of the manganese ions in the calcium silicate ceramic powder. The manganese-doped calcium silicate porous ceramic scaffold has high porosity, appropriate degradation speed and high mechanical strength, and is especially suitable for application in bone defect repair and photothermal therapy of bone tumors.
本发明公开锰掺杂硅酸钙多孔陶瓷支架及其制备方法和应用。所述锰掺杂硅酸钙多孔陶瓷支架是将含有锰离子的硅酸钙陶瓷粉体通过3D打印一体化成型制备的多孔结构支架；所述含有锰离子的硅酸钙陶瓷粉体中Mn占据部分Ca的位置但未改变硅酸钙的晶相，其中，Mn/（Mn+Ca）的摩尔比例为1‑10%；通过调节硅酸钙陶瓷粉体中锰离子的掺杂量调控多孔陶瓷支架的力学性能、降解性能、生物活性和光热性能。所述锰掺杂硅酸钙多孔陶瓷支架兼具高孔隙率、合适降解速度和高力学强度，尤其适合在骨缺损修复与光热治疗骨肿瘤的应用。
Manganese-doped calcium silicate porous ceramic scaffold and preparation method and application thereof
锰掺杂硅酸钙多孔陶瓷支架及其制备方法和应用
WU CHENGTIE (author) / CHEN LEI (author)
2021-08-20
Patent
Electronic Resource
Chinese
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