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A platform for research: civil engineering, architecture and urbanism
Hydroxyapatite/whitmanite bioactive ceramic scaffold composed of bionic natural bone ore and preparation method of hydroxyapatite/whitmanite bioactive ceramic scaffold
The invention relates to a hydroxyapatite/whitmanite bioactive ceramic scaffold composed of bionic natural bone ore and a preparation method of the hydroxyapatite/whitmanite bioactive ceramic scaffold. The preparation method of the scaffold comprises the following steps: uniformly dipping an organic polymer foam template in a slurry formed by hydroxyapatite and beta-tricalcium phosphate particles which are mixed in different proportions and a binder, carrying out high-temperature sintering to completely remove organic matters, and carrying out a hydrothermal reaction on the inorganic scaffold in an aqueous solution containing magnesium ions to obtain the scaffold. The hydroxyapatite/white calcium phosphate composite scaffold is obtained. The prepared composite ceramic scaffold is controllable in composition and degradation rate, excellent in mechanical property, free of cytotoxicity and remarkable in osteogenesis promoting effect, and the porosity of the scaffold is suitable for cell growth. The preparation method of the hydroxyapatite/whitmanite composite ceramic scaffold is simple and easy to implement, controllable in process and easy to amplify.
本发明涉及一种仿生天然骨矿组成的羟基磷灰石/白磷钙石生物活性陶瓷支架及其制备方法。这种支架的制备方法为，将有机高分子泡沫模板用不同比例混合的羟基磷灰石和β‑磷酸三钙颗粒与粘结剂组成的浆料均匀浸渍后，经高温烧结完全去除有机物后，使无机支架在含镁离子的水溶液中发生水热反应，得到羟基磷灰石/白磷钙石复合支架。本发明制备的复合陶瓷支架组成和降解速率可控，力学性能优良，支架孔隙率适于细胞进入生长，无细胞毒性且促成骨效果显著。该羟基磷灰石/白磷钙石复合陶瓷支架的制备方法简单易行，工艺可控，易于放大。
Hydroxyapatite/whitmanite bioactive ceramic scaffold composed of bionic natural bone ore and preparation method of hydroxyapatite/whitmanite bioactive ceramic scaffold
The invention relates to a hydroxyapatite/whitmanite bioactive ceramic scaffold composed of bionic natural bone ore and a preparation method of the hydroxyapatite/whitmanite bioactive ceramic scaffold. The preparation method of the scaffold comprises the following steps: uniformly dipping an organic polymer foam template in a slurry formed by hydroxyapatite and beta-tricalcium phosphate particles which are mixed in different proportions and a binder, carrying out high-temperature sintering to completely remove organic matters, and carrying out a hydrothermal reaction on the inorganic scaffold in an aqueous solution containing magnesium ions to obtain the scaffold. The hydroxyapatite/white calcium phosphate composite scaffold is obtained. The prepared composite ceramic scaffold is controllable in composition and degradation rate, excellent in mechanical property, free of cytotoxicity and remarkable in osteogenesis promoting effect, and the porosity of the scaffold is suitable for cell growth. The preparation method of the hydroxyapatite/whitmanite composite ceramic scaffold is simple and easy to implement, controllable in process and easy to amplify.
本发明涉及一种仿生天然骨矿组成的羟基磷灰石/白磷钙石生物活性陶瓷支架及其制备方法。这种支架的制备方法为，将有机高分子泡沫模板用不同比例混合的羟基磷灰石和β‑磷酸三钙颗粒与粘结剂组成的浆料均匀浸渍后，经高温烧结完全去除有机物后，使无机支架在含镁离子的水溶液中发生水热反应，得到羟基磷灰石/白磷钙石复合支架。本发明制备的复合陶瓷支架组成和降解速率可控，力学性能优良，支架孔隙率适于细胞进入生长，无细胞毒性且促成骨效果显著。该羟基磷灰石/白磷钙石复合陶瓷支架的制备方法简单易行，工艺可控，易于放大。
Hydroxyapatite/whitmanite bioactive ceramic scaffold composed of bionic natural bone ore and preparation method of hydroxyapatite/whitmanite bioactive ceramic scaffold
一种仿生天然骨矿组成的羟基磷灰石/白磷钙石生物活性陶瓷支架及其制备方法
CAI QING (author) / LI DAN (author) / DU ZHIYUN (author) / YANG XIAOPING (author)
2022-05-10
Patent
Electronic Resource
Chinese
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