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DETECTING TUMOR MUTATION BURDEN WITH RNA SUBSTRATE
Methods and compositions are provided for determining TMB in a tumor sample using transcriptome profiling data. Also provided herein are methods and compositions for determining the response of an individual with a specific TMB to a therapy such as immunotherapy.
DETECTING TUMOR MUTATION BURDEN WITH RNA SUBSTRATE
Methods and compositions are provided for determining TMB in a tumor sample using transcriptome profiling data. Also provided herein are methods and compositions for determining the response of an individual with a specific TMB to a therapy such as immunotherapy.
DETECTING TUMOR MUTATION BURDEN WITH RNA SUBSTRATE
MAYHEW GREG (author) / SHIBATA YOICHIRO (author) / LAI-GOLDMAN MYLA (author) / PEROU CHARLES (author) / PARKER JOEL (author)
2021-12-23
Patent
Electronic Resource
English
IPC:
G16B
Bias and inconsistency in the estimation of tumour mutation burden
| Springer Verlag | 2022