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Naked DNA Helicity Observed by Scanning Tunneling Microscopy

Cricenti, A. / Selci, S. / Felici, A. C. / Generosi, R. / Gori, E. / Djaczenko, W. / Chiarotti, G.

Abstract Uncoated DNA molecules marked with an activated Tris 1-Aziridinyl Phosphine Oxide (TAPO) solution were deposited on gold substrates and imaged in air with high resolution Scanning Tunneling Microscope (STM). Constant current and barrier height STM images show a clear evidence of the helicity of the DNA structure: pitch periodicity ranges between 25 and 34 Å while the average diameter is 20 Å. Molecular structure within a single helix turn is also observed.

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Naked DNA Helicity Observed by Scanning Tunneling Microscopy

Cricenti, A. / Selci, S. / Felici, A. C. / Generosi, R. / Gori, E. / Djaczenko, W. / Chiarotti, G.

Abstract Uncoated DNA molecules marked with an activated Tris 1-Aziridinyl Phosphine Oxide (TAPO) solution were deposited on gold substrates and imaged in air with high resolution Scanning Tunneling Microscope (STM). Constant current and barrier height STM images show a clear evidence of the helicity of the DNA structure: pitch periodicity ranges between 25 and 34 Å while the average diameter is 20 Å. Molecular structure within a single helix turn is also observed.

Naked DNA Helicity Observed by Scanning Tunneling Microscopy

Cricenti, A. / Selci, S. / Felici, A. C. / Generosi, R. / Gori, E. / Djaczenko, W. / Chiarotti, G.

Abstract Uncoated DNA molecules marked with an activated Tris 1-Aziridinyl Phosphine Oxide (TAPO) solution were deposited on gold substrates and imaged in air with high resolution Scanning Tunneling Microscope (STM). Constant current and barrier height STM images show a clear evidence of the helicity of the DNA structure: pitch periodicity ranges between 25 and 34 Å while the average diameter is 20 Å. Molecular structure within a single helix turn is also observed.

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Title:

Naked DNA Helicity Observed by Scanning Tunneling Microscopy

Contributors:

Cricenti, A. (author) / Selci, S. (author) / Felici, A. C. (author) / Generosi, R. (author) / Gori, E. (author) / Djaczenko, W. (author) / Chiarotti, G. (author)

Published in:

Scanning Tunneling Microscopy and Related Methods ; 359-365

NATO ASI Series ; 184

Publication date:

1990-01-01

Size:

7 pages

ISBN:

978-90-481-4075-6 , 978-94-015-7871-4

ISSN:

DOI:

https://doi.org/10.1007/978-94-015-7871-4_19

Type of media:

Article/Chapter (Book)

Type of material:

Electronic Resource

Language:

English

Keywords:

Barrier Height , Tunneling Microscopy , Tunneling Current , Tungsten Wire , Vibration Isolation Physics , Physics, general , Surfaces and Interfaces, Thin Films , Physical Chemistry , Biophysics and Biological Physics

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