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A platform for research: civil engineering, architecture and urbanism
Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model
The aim of this tutorial is to introduce the fundamental concepts of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling with a special focus on their practical implementation in a typical PBPK model building workflow. To illustrate basic steps in PBPK model building, a PBPK model for ciprofloxacin will be constructed and coupled to a pharmacodynamic model to simulate the antibacterial activity of ciprofloxacin treatment.
Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model
The aim of this tutorial is to introduce the fundamental concepts of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling with a special focus on their practical implementation in a typical PBPK model building workflow. To illustrate basic steps in PBPK model building, a PBPK model for ciprofloxacin will be constructed and coupled to a pharmacodynamic model to simulate the antibacterial activity of ciprofloxacin treatment.
Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model
Kuepfer, L (author) / Niederalt, C (author) / Wendl, T (author) / Schlender, J‐F (author) / Willmann, S (author) / Lippert, J (author) / Block, M (author) / Eissing, T (author) / Teutonico, D (author)
CPT: Pharmacometrics & Systems Pharmacology ; 5 ; 516-531
2016-10-01
16 pages
Article (Journal)
Electronic Resource
English
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