Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Polyphenol-calcium sulfate, bone cement material and preparation method thereof
According to the polyphenol-calcium sulfate, the bone cement material and the preparation methods of the polyphenol-calcium sulfate and the bone cement material, the polyphenol-calcium sulfate is prepared in an alcohol phase environment, the modification amount of polyphenol in the polyphenol-calcium sulfate is increased, and the prepared polyphenol-calcium sulfate has good antibacterial and antioxidant properties and stability. Metal is further compounded on the basis of polyphenol-calcium sulfate, the metal is mixed with an aqueous solution to prepare the bone cement material, the bone cement material is tested, and the test result shows that the bone cement material has good injectability, excellent oxidation resistance, antibacterial property, compressive strength and stability and strong operability, and can be used for preparing the bone cement material. The hydrogel has pH regulation degradation performance and good osteogenesis promoting performance, and shows responsiveness to inflammatory cells.
本申请提供了一种多酚‑硫酸钙、骨水泥材料及其制备方法，本申请通过在醇相环境中制备多酚‑硫酸钙，提高了多酚‑硫酸钙中多酚的修饰量，制备的多酚‑硫酸钙具有良好的抗菌抗氧化性和稳定性。本发明在多酚‑硫酸钙的基础上进一步复合金属，将其与水剂混合制备了骨水泥材料，对骨水泥材料进行测试，测试结果表明，该骨水泥材料具有良好的可注射性，优异的抗氧化性、抗菌性能、抗压强度和稳定性，可操作性强，具有pH调节降解性能和良好的促成骨性能，并且表现出对炎症细胞的响应性。
Polyphenol-calcium sulfate, bone cement material and preparation method thereof
According to the polyphenol-calcium sulfate, the bone cement material and the preparation methods of the polyphenol-calcium sulfate and the bone cement material, the polyphenol-calcium sulfate is prepared in an alcohol phase environment, the modification amount of polyphenol in the polyphenol-calcium sulfate is increased, and the prepared polyphenol-calcium sulfate has good antibacterial and antioxidant properties and stability. Metal is further compounded on the basis of polyphenol-calcium sulfate, the metal is mixed with an aqueous solution to prepare the bone cement material, the bone cement material is tested, and the test result shows that the bone cement material has good injectability, excellent oxidation resistance, antibacterial property, compressive strength and stability and strong operability, and can be used for preparing the bone cement material. The hydrogel has pH regulation degradation performance and good osteogenesis promoting performance, and shows responsiveness to inflammatory cells.
本申请提供了一种多酚‑硫酸钙、骨水泥材料及其制备方法，本申请通过在醇相环境中制备多酚‑硫酸钙，提高了多酚‑硫酸钙中多酚的修饰量，制备的多酚‑硫酸钙具有良好的抗菌抗氧化性和稳定性。本发明在多酚‑硫酸钙的基础上进一步复合金属，将其与水剂混合制备了骨水泥材料，对骨水泥材料进行测试，测试结果表明，该骨水泥材料具有良好的可注射性，优异的抗氧化性、抗菌性能、抗压强度和稳定性，可操作性强，具有pH调节降解性能和良好的促成骨性能，并且表现出对炎症细胞的响应性。
Polyphenol-calcium sulfate, bone cement material and preparation method thereof
一种多酚-硫酸钙、骨水泥材料及其制备方法
ZHANG PEIBIAO (Autor:in) / GUO MIN (Autor:in) / LI HAOXUAN (Autor:in) / ZHU YONGZHAN (Autor:in)
15.08.2023
Patent
Elektronische Ressource
Chinesisch
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