Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Eine Plattform für die Wissenschaft: Bauingenieurwesen, Architektur und Urbanistik
Multi-element doped fine-grain alumina-based ceramic used as implant and preparation method of multi-element doped fine-grain alumina-based ceramic
The invention belongs to the technical field of medical biological materials, and particularly relates to a multi-element doped fine-grain alumina-based ceramic used as an implant and a preparation method thereof.The preparation method comprises the steps that 75-85 parts of amorphous/gamma alumina, 1-25 parts of zirconium oxide, 0-6 parts of silicon dioxide, 0-5 parts of magnesium oxide, 0-5 parts of calcium oxide, 0-1 part of yttrium oxide and 0-2 parts of silver oxide are subjected to ball milling and spray granulation; performing dry pressing and cold isostatic pressing molding, and sequentially performing hot pressing sintering for 1.5-3 hours at the pressure of 200MPa and the temperature of 1050-1250 DEG C and microwave sintering or discharge plasma sintering post-treatment for 10-30 minutes at the temperature of 1300-1400 DEG C on a green body, so as to obtain the alumina-based biological ceramic which is 99.5% in density, high in strength and good in toughness, and can promote the combination of human tissues and a ceramic interface; the wound healing is accelerated, the postoperative infection risk is reduced, and the material can be used as a skeleton substitute material.
本发明属于医用生物材料技术领域，具体涉及一种用作植入体的多元素掺杂的细晶粒氧化铝基陶瓷及其制备方法，将无定形/γ氧化铝75‑85份，氧化锆1‑25，二氧化硅0‑6份，氧化镁0‑5份，氧化钙0‑5份，氧化钇0‑1份，氧化银0‑2份经过球磨、喷雾造粒后，进行干压、冷等静压成型，将生坯依次进行压力为200MPa，温度为1050℃‑1250℃热压烧结1.5‑3h，温度为1300℃‑1400℃微波烧结或放电等离子体烧结后处理10‑30min，得到的氧化铝基生物陶瓷致密度达到99.5％，强度高、韧性好，且能够促进人体组织与陶瓷界面的结合，加速伤口愈合，降低术后感染风险，可作为骨骼替代材料。
Multi-element doped fine-grain alumina-based ceramic used as implant and preparation method of multi-element doped fine-grain alumina-based ceramic
The invention belongs to the technical field of medical biological materials, and particularly relates to a multi-element doped fine-grain alumina-based ceramic used as an implant and a preparation method thereof.The preparation method comprises the steps that 75-85 parts of amorphous/gamma alumina, 1-25 parts of zirconium oxide, 0-6 parts of silicon dioxide, 0-5 parts of magnesium oxide, 0-5 parts of calcium oxide, 0-1 part of yttrium oxide and 0-2 parts of silver oxide are subjected to ball milling and spray granulation; performing dry pressing and cold isostatic pressing molding, and sequentially performing hot pressing sintering for 1.5-3 hours at the pressure of 200MPa and the temperature of 1050-1250 DEG C and microwave sintering or discharge plasma sintering post-treatment for 10-30 minutes at the temperature of 1300-1400 DEG C on a green body, so as to obtain the alumina-based biological ceramic which is 99.5% in density, high in strength and good in toughness, and can promote the combination of human tissues and a ceramic interface; the wound healing is accelerated, the postoperative infection risk is reduced, and the material can be used as a skeleton substitute material.
本发明属于医用生物材料技术领域，具体涉及一种用作植入体的多元素掺杂的细晶粒氧化铝基陶瓷及其制备方法，将无定形/γ氧化铝75‑85份，氧化锆1‑25，二氧化硅0‑6份，氧化镁0‑5份，氧化钙0‑5份，氧化钇0‑1份，氧化银0‑2份经过球磨、喷雾造粒后，进行干压、冷等静压成型，将生坯依次进行压力为200MPa，温度为1050℃‑1250℃热压烧结1.5‑3h，温度为1300℃‑1400℃微波烧结或放电等离子体烧结后处理10‑30min，得到的氧化铝基生物陶瓷致密度达到99.5％，强度高、韧性好，且能够促进人体组织与陶瓷界面的结合，加速伤口愈合，降低术后感染风险，可作为骨骼替代材料。
Multi-element doped fine-grain alumina-based ceramic used as implant and preparation method of multi-element doped fine-grain alumina-based ceramic
用作植入体的多元素掺杂的细晶粒氧化铝基陶瓷及其制备方法
CHEN ZHIHUI (Autor:in) / MA ZHONGMOU (Autor:in) / XIU YIRONG (Autor:in) / REN YURONG (Autor:in) / QIU JIANHUA (Autor:in)
05.11.2024
Patent
Elektronische Ressource
Chinesisch
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| Europäisches Patentamt | 2022