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Functionally-modified oligonucleotides and subunits thereof
Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3' and/or 5'-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
Functionally-modified oligonucleotides and subunits thereof
Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3' and/or 5'-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
Functionally-modified oligonucleotides and subunits thereof
HANSON GUNNAR J (author) / WELLER DWIGHT D (author) / CAI BAO ZHONG (author) / ZHOU MING (author)
2016-11-24
Patent
Electronic Resource
English
IPC:
C04B
Kalk
,
LIME
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