A platform for research: civil engineering, architecture and urbanism
A platform for research: civil engineering, architecture and urbanism
FUNCTIONALLY-MODIFIED OLIGONUCLEOTIDES AND SUBUNITS THEREOF
I:\Interwov \NRPortbI\DCC\ANIl\20040356_L.docx-3/03/2020 Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3' and/or 5'-end groups are provided. The disclosed 5 compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
FUNCTIONALLY-MODIFIED OLIGONUCLEOTIDES AND SUBUNITS THEREOF
I:\Interwov \NRPortbI\DCC\ANIl\20040356_L.docx-3/03/2020 Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3' and/or 5'-end groups are provided. The disclosed 5 compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
FUNCTIONALLY-MODIFIED OLIGONUCLEOTIDES AND SUBUNITS THEREOF
HANSON GUNNAR J (author) / WELLER DWIGHT D (author) / CAI BAO ZHONG (author) / ZHOU MING (author)
2020-04-23
Patent
Electronic Resource
English
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