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Method for printing porous biological ceramic bone tissue engineering scaffold by utilizing sacrificial material
The invention discloses a method for printing a porous biological ceramic bone tissue engineering scaffold by using a sacrificial material. The method comprises the following steps: S1, constructing a 3D printing model: obtaining a 3D printing model of a bone tissue engineering scaffold with different pore structures through a 3D printing technology, and planning a printing path; S2, printing the bone tissue engineering scaffold according to the planned path: performing synchronous and coordinated printing by using double nozzles, wherein one nozzle sprays out a filiform biological ceramic material, and the other nozzle sprays out a supporting materials between the adjacent filiform biological ceramic materials; S3, sequentially carrying out air drying and sintering treatment on the printed bone tissue engineering scaffold, and removing the supporting material to form the biological ceramic bone tissue engineering scaffold with different pore structures. In the printing process, the problem that the hole diameter becomes small due to droop of the biological ceramic wires is solved through the supporting material, so that accurate printing of the upper-layer material is guaranteed, and then biological ceramic bone tissue engineering scaffolds of different hole structures can be printed.
本发明公开一种利用牺牲材料打印多孔生物陶瓷骨组织工程支架的方法,其包括以下步骤:S1:构建3D打印模型:通过3D打印技术获取带有不同孔隙结构的骨组织工程支架的3D打印模型,并规划打印路径;S2:按照规划路径打印骨组织工程支架:利用双喷头同步协调打印,其中一个喷头喷出丝状生物陶瓷材料,另一个喷头在相邻丝状生物陶瓷材料之间喷出支撑材料;S3:对打印出来的骨组织工程支架依次进行风干和烧结处理,去除支撑材料,形成带不同孔隙结构的生物陶瓷骨组织工程支架。本发明在打印过程中通过支撑材料解决生物陶瓷丝下垂引起的孔径变小的问题,从而保证上层材料的精确打印,进而能够打印不同孔隙结构生物陶瓷骨组织工程支架。
Method for printing porous biological ceramic bone tissue engineering scaffold by utilizing sacrificial material
The invention discloses a method for printing a porous biological ceramic bone tissue engineering scaffold by using a sacrificial material. The method comprises the following steps: S1, constructing a 3D printing model: obtaining a 3D printing model of a bone tissue engineering scaffold with different pore structures through a 3D printing technology, and planning a printing path; S2, printing the bone tissue engineering scaffold according to the planned path: performing synchronous and coordinated printing by using double nozzles, wherein one nozzle sprays out a filiform biological ceramic material, and the other nozzle sprays out a supporting materials between the adjacent filiform biological ceramic materials; S3, sequentially carrying out air drying and sintering treatment on the printed bone tissue engineering scaffold, and removing the supporting material to form the biological ceramic bone tissue engineering scaffold with different pore structures. In the printing process, the problem that the hole diameter becomes small due to droop of the biological ceramic wires is solved through the supporting material, so that accurate printing of the upper-layer material is guaranteed, and then biological ceramic bone tissue engineering scaffolds of different hole structures can be printed.
本发明公开一种利用牺牲材料打印多孔生物陶瓷骨组织工程支架的方法,其包括以下步骤:S1:构建3D打印模型:通过3D打印技术获取带有不同孔隙结构的骨组织工程支架的3D打印模型,并规划打印路径;S2:按照规划路径打印骨组织工程支架:利用双喷头同步协调打印,其中一个喷头喷出丝状生物陶瓷材料,另一个喷头在相邻丝状生物陶瓷材料之间喷出支撑材料;S3:对打印出来的骨组织工程支架依次进行风干和烧结处理,去除支撑材料,形成带不同孔隙结构的生物陶瓷骨组织工程支架。本发明在打印过程中通过支撑材料解决生物陶瓷丝下垂引起的孔径变小的问题,从而保证上层材料的精确打印,进而能够打印不同孔隙结构生物陶瓷骨组织工程支架。
Method for printing porous biological ceramic bone tissue engineering scaffold by utilizing sacrificial material
利用牺牲材料打印多孔生物陶瓷骨组织工程支架的方法
SUO HAIRUI (author) / YANG HAN (author)
2021-12-10
Patent
Electronic Resource
Chinese
IPC:
C04B
Kalk
,
LIME
/
A61F
FILTERS IMPLANTABLE INTO BLOOD VESSELS
,
Filter in Blutgefäße implantierbar
/
B33Y
ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
,
Additive (generative) Fertigung, d. h. die Herstellung von dreidimensionalen [3D] Bauteilen durch additive Abscheidung, additive Agglomeration oder additive Schichtung, z. B. durch 3D- Drucken, Stereolithografie oder selektives Lasersintern
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