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Bone tissue engineering scaffold 3D printing material with piezoelectric property
The invention belongs to the technical field of biomedical materials, and particularly relates to a bone tissue engineering scaffold 3D printing material with piezoelectric property. The material takes a polyvinyl alcohol aqueous solution, barium titanate and hydroxyapatite as main raw materials. The 3D printing material with moderate viscosity and uniform distribution can be obtained without adding auxiliary materials such as a surfactant and a defoaming agent; the bone tissue engineering scaffold obtained after printing is good in structure retention capacity, and meanwhile, the cell activity can be well maintained. Besides, under the stimulation of proper external mechanical force, charges are generated on the surface of the stent to promote the growth of bone tissues and the formation of blood vessels, so that the material is very suitable for preparing bone repair materials. The preparation method of the bone tissue engineering scaffold is simple, different morphologies can be prepared according to different injured parts of patients, and the application range is expanded.
本发明属于生物医用材料技术领域，具体涉及一种具有压电性能的骨组织工程支架3D打印材料。该材料以聚乙烯醇水溶液、钛酸钡、羟基磷灰石为主要原料，无需添加表面活性剂、除泡剂等辅料，即可得到粘度适中、均匀分布的3D打印材料，打印后所得骨组织工程支架结构保持能力较好，同时还能很好地保持细胞活性，在适当的外界机械力刺激下，在支架表面产生电荷，促进骨组织的生长及血管的形成，非常适用于制备骨修复材料；并且本发明骨组织工程支架制备方法简单，可针对不同的患者损伤部位制备出不同的形貌，使用范围广。
Bone tissue engineering scaffold 3D printing material with piezoelectric property
The invention belongs to the technical field of biomedical materials, and particularly relates to a bone tissue engineering scaffold 3D printing material with piezoelectric property. The material takes a polyvinyl alcohol aqueous solution, barium titanate and hydroxyapatite as main raw materials. The 3D printing material with moderate viscosity and uniform distribution can be obtained without adding auxiliary materials such as a surfactant and a defoaming agent; the bone tissue engineering scaffold obtained after printing is good in structure retention capacity, and meanwhile, the cell activity can be well maintained. Besides, under the stimulation of proper external mechanical force, charges are generated on the surface of the stent to promote the growth of bone tissues and the formation of blood vessels, so that the material is very suitable for preparing bone repair materials. The preparation method of the bone tissue engineering scaffold is simple, different morphologies can be prepared according to different injured parts of patients, and the application range is expanded.
本发明属于生物医用材料技术领域，具体涉及一种具有压电性能的骨组织工程支架3D打印材料。该材料以聚乙烯醇水溶液、钛酸钡、羟基磷灰石为主要原料，无需添加表面活性剂、除泡剂等辅料，即可得到粘度适中、均匀分布的3D打印材料，打印后所得骨组织工程支架结构保持能力较好，同时还能很好地保持细胞活性，在适当的外界机械力刺激下，在支架表面产生电荷，促进骨组织的生长及血管的形成，非常适用于制备骨修复材料；并且本发明骨组织工程支架制备方法简单，可针对不同的患者损伤部位制备出不同的形貌，使用范围广。
Bone tissue engineering scaffold 3D printing material with piezoelectric property
一种具有压电性能的骨组织工程支架3D打印材料
ZHOU MIAO (author) / CHEN SI (author) / GUO KAI (author) / LI SHUYI (author) / GENG YUANMING (author)
2022-01-25
Patent
Electronic Resource
Chinese
IPC:
C04B
Kalk
,
LIME
/
A61F
FILTERS IMPLANTABLE INTO BLOOD VESSELS
,
Filter in Blutgefäße implantierbar
/
B33Y
ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
,
Additive (generative) Fertigung, d. h. die Herstellung von dreidimensionalen [3D] Bauteilen durch additive Abscheidung, additive Agglomeration oder additive Schichtung, z. B. durch 3D- Drucken, Stereolithografie oder selektives Lasersintern
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Tissue Engineering Scaffold Material and New Bone Growth
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Bone tissue repair material and preparation method of bone tissue engineering scaffold
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Bone tissue repair material and preparation method of tissue engineering scaffold
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Preparation method of hydroxyapatite bone tissue engineering scaffold
| European Patent Office | 2023