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A platform for research: civil engineering, architecture and urbanism
Application of Electrospun Materials in Gene Delivery
Gene therapy has emerged as a promising strategy for treatment of many acquired or inherited diseases providing ample benefits over conventional therapies. Even the cost factor and stability are attractive with gene therapy than majority of the protein formulations. It is a successful combination of gene delivery technologies with the electrospinning methods to enhance the potential of gene therapy in several biomedical and pharmaceutical applications like cancer treatment, stem cell treatment, chronic genetic disorders, and tissue engineering. Electrospun nanofibrous scaffolds area is the leading research field in gene therapy with their advantageous characteristics utilizing the available categories of polymers. In this chapter, detailed information about gene therapy, comparison of viral with non‐viral vectors, electrospinning methods, materials useful for nanofibrous scaffolds fabrication, characterization of those scaffolds, applications of scaffolds in gene delivery, their significant role, marketed products, present challenges, and future scope will be provided.
Application of Electrospun Materials in Gene Delivery
Gene therapy has emerged as a promising strategy for treatment of many acquired or inherited diseases providing ample benefits over conventional therapies. Even the cost factor and stability are attractive with gene therapy than majority of the protein formulations. It is a successful combination of gene delivery technologies with the electrospinning methods to enhance the potential of gene therapy in several biomedical and pharmaceutical applications like cancer treatment, stem cell treatment, chronic genetic disorders, and tissue engineering. Electrospun nanofibrous scaffolds area is the leading research field in gene therapy with their advantageous characteristics utilizing the available categories of polymers. In this chapter, detailed information about gene therapy, comparison of viral with non‐viral vectors, electrospinning methods, materials useful for nanofibrous scaffolds fabrication, characterization of those scaffolds, applications of scaffolds in gene delivery, their significant role, marketed products, present challenges, and future scope will be provided.
Application of Electrospun Materials in Gene Delivery
Inamuddin (editor) / Boddula, Rajender (editor) / Ahamed, Mohd Imran (editor) / Asiri, Abdullah M. (editor) / Rao, GSN Koteswara (author) / Kurakula, Mallesh (author) / Yadav, Khushwant S. (author)
2020-04-14
42 pages
Article/Chapter (Book)
Electronic Resource
English
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